When Xiao Wang applied to faculty jobs, many of the institutions where she interviewed thought her research proposal - to ...

with complementary sequences in the ribosome-bound mRNA. The conserved GTPase OLA1 participates in translation. Here, authors demonstrate its role in alleviating translation stalling on D/E-rich ...

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is read by ribosomes to generate protein (translation). Biologically active RNAs ...

Oligonucleotide therapies are among the most promising biological therapeutics. They target disease at a different stage of ...

Yale researchers have created "Ochre," a genomically recoded organism that enables the production of synthetic proteins with ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

Serpine1 mRNA-binding protein 1 (SERBP1 ... with proteins in specific nuclear complexes implicated in splicing regulation, cell division, and ribosome biogenesis. Approximately a third of ...

Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to ...

In principle, mRNA vaccines are ideal for health emergencies as they can be quickly mass produced using a template. The problem is that current cell-based template production methods take too long, ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...