The VDR is a member of the steroid/hormone nuclear receptor superfamily that includes 48 ligand-activated transcription factors. [3] These factors bind to conserved elements in the promoters of genes ...

Tsukuba, Japan—Bile ducts are pathways that carry hepatocyte-produced bile from the liver to the small intestine. In the human fetal liver, bile ducts are formed from bile duct epithelial cells ...

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce ...

Scientists find how changes in bile acids linked to gut bacteria may signal advancing chronic kidney disease, pointing to a possible link between gut metabolism and kidney decline ...

New research links altered bile acids to chronic kidney disease progression, highlighting potential metabolic pathways ...