Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

While it is accepted that extracellular vesicles (EVs)-mediated transfer of microRNAs contributes to intercellular communication, the knowledge about molecular mechanisms controlling the selective and ...

In this study, a multifunctional tetrahedral DNA nanostructure (MTDN) was constructed by assembling different functional modules for the simultaneous sensitive detection and imaging of targets ...

mRNA vaccines work differently: The antigen is produced inside the body. The vaccine itself consists of a small piece of genetic code—messenger RNA (mRNA)—to which the immune system responds.

Lipid nanoparticles (LNPs) have shown great promise for nucleic acid drug delivery. Canonical LNPs consist of four lipid components: ionizable lipid, cholesterol, Polyethylene glycol-yl-lipid ...

The Trump administration's cancellation of $766 million in contracts to develop mRNA vaccines against potential pandemic flu viruses is the latest blow to national defense, former health security ...

A GROUNDBREAKING approach using mRNA-lipid nanoparticle technology has shown the ability to force HIV out of its latent state, offering hope for future curative therapies. Latent HIV, harboured in ...

President Trump’s administration has slammed the brakes on development of messenger RNA (mRNA) vaccines, which proved their lifesaving potential during the COVID-19 pandemic but have come und… ...

Although lipid nanoparticles (LNPs) and other systems have demonstrated success in delivering siRNA and mRNA vaccines, miRNA delivery remains suboptimal. Early clinical trials using LNPs for miRNA ...

An mRNA-based diagnostic test is being developed that could catch cancers earlier, when they're more treatable. But this innovation is under threat.