pharmaphorum10d
The critical bioanalytical strategies unlocking the potential of LNP-mRNA
The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...
Phys.org on MSN8d
The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA
The spliceosome then converts them into mature, functional mRNA. To do this, this large protein-RNA complex ... The proteins ...
AZoLifeSciences on MSN8d
How Proteins Are Made: From DNA to Function
Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...
The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
Science Daily19h
Splicing twins: Unraveling the secrets of the minor spliceosome complex
Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
Nature8d
The end defines the means in bacterial mRNA decay
In eukaryotes, the process of mRNA decay generally involves loss of the 3′ poly(A) tail and removal of the cap by a decapping enzyme (Dcp2). The body of the mRNA is then degraded from the 5 ...
Armed robbery in Revesby8d
Spliceosome: Cells' Error-Free MRNA Production Explained
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
News Medical on MSN3d
EMBL researchers reveal new structural insights into minor spliceosome function
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...