The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

In a study of human immune cells infected with HIV, the virus that causes AIDS, scientists at Johns Hopkins Medicine say a ...

The growing incidence of infectious diseases, cancer, and chronic illnesses has substantially increased the demand for ...

Luton, Bedfordshire, United Kingdom, June 16, 2025 (GLOBE NEWSWIRE) -- The global mRNA vaccine core enzyme market is witnessing unprecedented growth, driven by heightened demand for rapid vaccine ...

– MT-302 and MT-303 embody the first clinical applications of in vivo mRNA CAR therapies administered systemically – – Initial translational results support proof-of-mechanism with immune ...

The preclinical company’s lead asset uses lipid nanoparticles to deliver mRNA to liver cells that codes for transcription factors known to make hepatocytes look—and act—younger, NewLimit co ...

Transcription of DNA into mRNA and translation of mRNA into proteins are two major processes underlying gene expression. Due to the distinct molecular mechanisms, timings, and locales of action, these ...

This suggests that mRNA moving between different mammalian stem cells has biologically significant effects beyond mere movement, going as far as cell fate conversion. The team also identified several ...

Discover how they make in vitro transcription possible and refine reaction products to generate highly pure, homogeneous mRNA. Learn more about: The critical stages of mRNA synthesis ...

Plus, the Ntensify solution works with any mRNA construct, and it is processed through one-pot in vitro transcription with co-transcriptional capping and a redesigned single-step purification to ...

But in the cirrhotic livers they examined, HNF4 alpha was almost nonexistent. The team needed a way to get the transcription factor into liver cells, so they turned to mRNA technology.

However, understanding the relative contributions of mRNA transcription and degradation to shaping these profiles has been challenging, particularly within embryos with diverse cellular identities.