LncRNAs and circRNAs are key regulators of gene expression, influencing disease mechanisms and offering potential as ...

X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in ...

This useful study presents findings on the developmental roles of Nup107, a key nucleoporin, in regulating the larval-to-pupal transition in Drosophila melanogaster through its involvement in ecdysone ...

Discovering ultra-conserved elements in the genome and their role in limiting protein production in mice testes.

Compared with other protein-selection techniques, mRNA display provides the advantages listed in the following section. Easy & Robust Recovery of the Selected Polypeptide Sequences & Freedom of ...

Modeling interrogates all possible combinations of two binding sites across the provided sequence space and generates a measure of the ∆G mRNA:RsmA for each combination, per gene. These are then ...

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein ...

Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system. Nature Materials , 2025; DOI: 10.1038/s41563-024-02114-5 Cite This Page : ...

A lipid nanoparticle system has been developed to deliver mRNA across the blood-brain barrier via intravenous injection, overcoming a significant challenge in treating brain diseases.

New York, NY [February 17, 2025]—Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via ...