"It is striking that in both mice and humans, the same miRNA binds in two places on the SRL mRNA,", said Marzluff, ...

Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is characterized by memory and physical impairment in aged individuals. microRNAs (miRNAs) are small, single-stranded noncoding ...

The RISC, guided by the miRNA, binds to complementary sequences in the 3' untranslated region (UTR) of target messenger RNAs (mRNAs). This binding leads to translational repression or mRNA degradation ...

This study presents a new prognostic model using mitophagy-related genes (MRGs) in glioma, a type of brain tumor, developed through bioinformatics. The model seeks to improve the understanding of ...

The mRNA targets of miRNA can be determined by using bioinformatics methods and bioassays for monitoring the amounts of target mRNA. In plants, miRNA binding sites are usually found in the coding ...

1 This means miRNA guides can target any mRNA with homology to its seed region, even if the rest of the sequence is not a match. This promiscuous binding activity means that miRNA can act on many ...

By Kim Seon Ah Domestic researchers have developed a technology for early diagnosis of lung cancer with just a few drops of ...

The kit purifies all sizes of RNA, from large mRNA and ribosomal RNA down to microRNA (miRNA). The RNA is preferentially purified from other cellular components such as proteins, without the use ...

"Every microRNA regulates several genes," said Kämpe. "And each mRNA is regulated by many distinct microRNAs, creating a robust system for gene regulation." When did RNA enter the public spotlight?