Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...
Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
In eukaryotes, the process of mRNA decay generally involves loss of the 3′ poly(A) tail and removal of the cap by a decapping enzyme (Dcp2). The body of the mRNA is then degraded from the 5 ...
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
Researchers have revealed the structure of U11 snRNP – one of the five subunits of the minor spliceosome, which initiates the intron selection process.