Background The evidence on associations between ultra-processed foods (UPF) and lung cancer risk is limited and inconsistent.

Background The evidence on associations between ultra-processed foods (UPF) and lung cancer risk is limited and inconsistent. Research question Are UPF associated with an increased risk of lung cancer ...

Circulating miRNAs and childhood asthma ICS response: a stratified analysis in the intervention arm of an RCT with vitamin D effect modification ...

Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with increased morbidity and mortality. The effective management of COPD exacerbations awaits a better understanding of the ...

BACKGROUND Guidelines state that oral and inhaled corticosteroids are the cornerstone of asthma treatment. The effect of both types of treatment can be assessed by measuring lung and systemic ...

The clinical presentation of Aspergillus lung disease is determined by the interaction between fungus and host. Invasive aspergillosis develops in severely immunocompromised patients, including those ...

Rationale OPEP devices are often used therapeutically in order to aid airway clearance where excess mucus is a challenge, such as in bronchiectasis, CF and COPD. Ease of use, ability to clean and ...

In vitro testing has shown that nicotine may play a role in making cancers more aggressive,1 but the currently available evidence does not suggest that nicotine in itself induces cancer.2 Despite this ...

There remain many treatment uncertainties in cystic fibrosis (CF). With limited resources, research should focus on questions which are most important to the CF community. We conducted a James Lind ...

Introduction Over one million children have asthma in the UK and a recognised need for support transitioning into adult services. Poor transition with uncoordinated processes risks disengagement from ...

BACKGROUND Pulmonary rehabilitation programmes improve the health of patients disabled by lung disease but their cost effectiveness is unproved. We undertook a cost/utility analysis in conjunction ...

Epidemiological and prevalence data for chronic sinusitis are relatively rare. In children, in particular, the precise incidence of chronic sinusitis has not been established. This paucity of ...