A newly engineered antibody can penetrate kidney cysts and interrupt the growth signals that drive polycystic kidney disease.

PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...

That's what 61-year-old retiree Christine Chia has had to grapple with since she was diagnosed with polycystic kidney disease ...

Polycystic kidney disease (PKD) is a genetic disorder marked by the growth of many fluid-filled sacs (cysts) in your kidneys. These cysts can grow to replace normal kidney tissue over time, leading to ...

A diagnosis of polycystic kidney disease does not preclude good nutrition. Clinicians should guide patients toward safer and healthier eating.

Bill Reh lived with his kidney disease for decades, not needing a transplant until earlier this year. A donor match was found ...

Now, the veteran and former paramedic needs help from others to survive. “Oh, I eat these like candy,” he said while holding a container of pills. “Breakfast of champions, I call it. I take 13 pills ...

The Polycystic Kidney Disease Foundation and IQVIA are partners in the development of the ADPKD Registry, which is tracking longitudinal quality-of-life information from patients across North America.

A three-month clinical study on dietary interventions to help treat polycystic kidney disease (PKD) indicates that not only is dietary intervention feasible, it also appears to have resulted in ...

Please provide your email address to receive an email when new articles are posted on . Of the included patients, 2.5% were on dialysis and 23% had a kidney transplant. Autosomal dominant PKD affects ...

Data from this Australian study showed a higher prevalence of intracranial aneurysms (ICAs) in patients with ADPKD compared with the general population. Many patients in the study had no known risk ...

The approach should be individualized to each patient, says Dr. David Charytan of the NYU Grossman School of Medicine. Here's why. (3:28) Before receiving a kidney transplant, patients with autosomal ...