Mapping how Narcan reverses opioid overdose can provide a molecular blueprint for developing more effective drugs against ...
Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States' fight against the ...
The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, ...
Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...
Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced “mew-opioid”) receptors. What they didn’t know — until now — was ...
Studies by an international research team suggest that targeting the delta opioid receptor may represent an approach to treating chronic inflammatory pain that has fewer side effects than the use of ...
We report that opioids from the inflamed colon activate δ-opioid receptors (DOPr) in endosomes of nociceptors. Biopsy samples of inflamed colonic mucosa from patients and mice with colitis released ...
Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) have developed a novel molecule that binds to and blocks a previously unrecognized opioid receptor ...
BINGHAMTON, N.Y. -- A five-year, $2.59 million grant from the National Institutes of Health will allow a psychology professor at Binghamton University, State University of New York to study the ...
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