A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...
New findings indicate that transfer RNA (tRNA) has another function in addition to its long-established role in gene expression. tRNA also helps control apoptosis, or programmed cell death, according ...
tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 18 (May 3, 2016), pp. 4994-4999 (6 pages) During translation, a plethora of protein factors bind to the ...
The human genome includes more than 500 genes for transfer RNA (tRNA) molecules, which are essential for making proteins in all living organisms. Scientists have long understood the fundamental role ...
Mycoplasma leucyl-tRNA synthetases (LeuRSs) have been identified in which the connective polypeptide 1 (CP1) amino acid editing domain that clears mischarged tRNAs are missing (Mycoplasma mobile) or ...
IRE1α-driven production of 5’-tRH-Gly GCC during ER stress, aiding cellular adaptation in various eukaryotic organisms, ranging from yeast to humans To fill this knowledge gap, a group of researchers ...
Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...
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