The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

The journey of mRNA begins in the cell nucleus, where it is synthesized through a process called transcription: Through this process, mRNA serves as the critical link between the genetic information ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

2 Located throughout the pre-mRNA are short, cis-acting motifs consisting of five to six nucleotides that are binding sites for RBP, which act in trans. 1,8 “When an exon that is alternatively spliced ...

templates for in vitro transcription (IVT) synthesis of mRNA molecules. Alchemy cell-free DNA technology is now available at research grade, providing researchers with a faster, more efficient ...

By analyzing ERBB2 mRNA expression data, researchers identified a group of HER2-negative patients with poor outcomes and potential markers of treatment resistance.

We found that inclusion or exclusion of the 3′UTR of an mRNA that encodes a transcription factor did not change how much of the transcription factor protein was expressed but determined the location ...

Preventing the cell's protein factories from making the notorious cancer-causing protein MYC could stop out-of-control tumors.

There have been 67 confirmed human bird flu cases in the U.S. since April 2024. Moderna has been awarded approximately $590 million from the federal government to help speed up the development of ...