Nature13y
Chemical Structure of RNA
Because of this flexibility, the 30 to 40 tRNAs present in a cell can "read" all 61 codons in mRNA. The opposite end of the folded structure, which is the 3' end of the tRNA, binds to its ...
The Scientist3mon
Probing the Structure of mRNA Molecules
The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...
Nature4y
Translation: DNA to mRNA to Protein
Translation Begins After the Assembly of a Complex Structure The translation of mRNA begins with the formation of a complex on the mRNA (Figure 4). First, three initiation factor proteins (known ...
News Medical on MSN11mon
Boosting mRNA activity and longevity with multi-tailed structures
Based on previous research, Wang and Chen knew that one part of mRNA's structure, a branch called the poly(A) tail, plays an ...
mskcc.org4y
RNA ligases and RNA repair
RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...
Science Daily12d
Cell connects: Breaking barriers in stem cell communication through mRNA transfer
Messenger RNA can travel between different types of stem cells through tunnel-like structures, as revealed by a new study. By studying interactions between mouse and human stem cells, they discovered ...
The Scientist2y
Mammalian Oocytes Store mRNA in Newly Found Membraneless Structure
These molecules cluster around mitochondria throughout the cytoplasm, forming a structure the team named the mitochondria ... which had been previously associated with oocyte maturation and mRNA ...
Hosted on MSN28d
The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In this study, the researchers reveal the structure of U11 snRNP—one of the five subunits ... information—called introns—from the precursors of messenger RNA (pre-mRNA), the molecule responsible for ...
mskcc.org22d
In Early-Phase Pancreatic Cancer Clinical Trial, Investigational mRNA Vaccine Induces Sustained Immune Activity in Small Patient Group
Dr. Vinod Balachandran says mRNA vaccines could stimulate the immune system to recognize and attack pancreatic cancer cells. An experimental approach to treating pancreatic cancer with the messenger ...
Pfizer and BioNTech COVID vaccine broke patent: German court
A German court found Wednesday that American pharmaceutical giant Pfizer and German firm BioNTech violated a patent to make ...
Medical Xpress23d
mRNA research explores new frontiers in celiac disease treatment
One possible answer to that life-changing question? New research is using messenger RNA (mRNA) led by Penn Medicine's Drew Weissman, MD, Ph.D., the Roberts Family Professor of Vaccine Research and ...