DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...

Researchers have identified a molecular brake that limits DNA replication in healthy cells, revealing how cells prevent a long-suspected replication catastrophe and pointing to a potential ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

Researchers have found that the “mother” of all stem cells, known as totipotent stem cells, have a much slower rate of DNA replication, which helps improve their efficiency at differentiating into ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only. This limits the potential use of adult cells for ...