Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of the most significant developments in optics. Due to the wave nature of light ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

Summary: A research team reports the development of a high-resolution, adaptive light-sheet microscopy system capable of ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a ...

From overcoming classical optical limits to tracking single proteins in real time, super-resolution imaging continues to ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...