Many people with tough-to-treat depression may be trying psilocybin, the active ingredient in magic mushrooms, as an alternative to antidepressants. Thinking that it's a "natural" drug, folks might ...

"Magic" mushrooms achieve their psychedelic effects by temporarily scrambling a brain network involved in introspective thinking like daydreaming and remembering, a new study reports. Brain scans of ...

A new study suggests that a moderate dose of psilocybin can effectively reduce symptoms of obsessive-compulsive disorder for ...

More commonly known as a way to get high, the active ingredient of magic mushrooms may provide benefits previously unknown. Psilocybin, the psychedelic chemical that causes euphoria and hallucinations ...

“We are in the middle of a rapidly evolving cultural, media, and legal landscape when it comes to psychedelics,” says Nora D. Volkow, M.D., director of the National Institute on Drug Abuse (NIDA).

After comparing the long-term effects of the psychedelic psilocybin and a commonly prescribed antidepressant, new research found that both significantly reduced depression. However, psilocybin ...

A new study shows that natural mushroom extracts may be more therapeutically effective than synthesized psilocybin, which is widely used in research investigating the medicinal potential of the ...

People in a new study who took psilocybin often experienced headache, nausea, anxiety, dizziness and elevated blood pressure -- side effects similar to those seen with regular antidepressants. Photo ...