Switching from an SSRI to an SNRI typically involves gradually tapering off the SSRI under a doctor’s guidance and starting the SNRI at a low dose. Switching from a selective serotonin reuptake ...

LAS VEGAS, NV — Vincent Brett, MS, PharmD, of Janssen Scientific Affairs, Raritan, NJ, and colleagues presented a post-hoc analysis of pooled safety data at PAINWeek 2012, and found that adding ...

September 24, 2012 (Phoenix, Arizona) — Tricyclic antidepressants (TCAs) show greater efficacy than serotonin norepinephrine reuptake inhibitors (SNRIs) in the treatment of chronic pain related to ...

Results showed that discontinuation of any SNRI was associated with withdrawal symptoms, with the highest prevalence linked to venlafaxine and desvenlafaxine. Serotonin-noradrenaline reuptake ...

Esketamine combined with a serotonin-norepinephrine reuptake inhibitor (SNRI) for treatment-resistant depression (TRD) was linked to significantly lower rates of several adverse outcomes than ...

(Montreal, June 27, 2002)—People with social anxiety disorder (SAD), also known as social phobia, significantly reduced their fear, anxiety and related symptoms in four or six weeks of treatment with ...

Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressants that block the reuptake of both serotonin and norepinephrine in the body. They are taken to treat depression, ...

Desvenlafaxine, the major active metabolite of venlafaxine (Effexor XR, also from Wyeth), is a potent and selective SNRI. The increase in the effects of these neurotransmitters in the central nervous ...

ROCKVILLE, Md., July 20 -- Mixing common migraine drugs such as Imitrex (sumatriptan) with antidepressants like Prozac (fluoxetine) or Cymbalta (duloxetine) can trigger a life-threatening condition ...

Users of selective serotonin reuptake inhibitors had a higher risk of hyponatremia than users of serotonin-norepinephrine reuptake inhibitors, especially with concurrent thiazide diuretic treatment.