Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during gene expression, findings that may inform the ...

The findings demonstrate that, under certain circumstances, the RNA polymerase (RNAP) enzyme responsible for copying DNA into RNA can generate rampant R-loops—if not for the intervention of a ...

Centrosomes are nonmembrane organelles and responsible for microtubule nucleation and organization. Centrosomal RNAs have been identified in diverse model systems and are known to regulate gene ...

Synthetic biologists working with DNA and RNA often run into an unhelpful nemesis called T7 RNA polymerase enzyme, which Lucks compares to the radio battery for its role in pumping out output signals.

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...