Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA ...
The vivid wing patterns of butterflies, once attributed to a gene, are now traced to an overlooked microRNA.
1 This means miRNA guides can target any mRNA with homology to its seed region, even if the rest of the sequence is not a match. This promiscuous binding activity means that miRNA can act on many ...
The mRNA targets of miRNA can be determined by using bioinformatics methods and bioassays for monitoring the amounts of target mRNA. In plants, miRNA binding sites are usually found in the coding ...
"It is striking that in both mice and humans, the same miRNA binds in two places on the SRL mRNA,", said Marzluff, co-director of the UNC RNA Discovery Center. "This miRNA reduces the ability ...
The RISC, guided by the miRNA, binds to complementary sequences in the 3' untranslated region (UTR) of target messenger RNAs (mRNAs). This binding leads to translational repression or mRNA degradation ...
The kit purifies all sizes of RNA, from large mRNA and ribosomal RNA down to microRNA (miRNA). The RNA is preferentially purified from other cellular components such as proteins, without the use ...
There are a number of ongoing microRNA trials aimed at combating cancer ... Go deeper: Scientists behind mRNA vaccines win Nobel Prize in Medicine Editor's note: This story was corrected to ...