University of Pittsburgh School of Medicine researchers carrying out a small pilot clinical trial demonstrating that a drug-free, minimally invasive intervention targets the root cause of progressive ...

Repeated exercise, or wasting, can change the way key genes work.

Muscle atrophy is a primary characteristic of both sarcopenia and cachexia, significantly impacting physical function and quality of life. This figure illustrates the multifaceted causes of muscle ...

The loss of muscle mass, or muscle atrophy, is a relatively common condition in today's aging and increasingly sedentary societies. While the disuse of muscles is the most frequent catalyst for muscle ...

HOUSTON – A newly identified gene, atrogin-1, is involved in muscle loss associated with cancer, diabetes, fasting and kidney disease as well as in the atrophy occurring with disuse, inactivity, and ...

For most of us, everyday life is characterized by a lack of movement. But those long hours sitting at a desk, commuting by car or public transport, and spending leisure time in front of screens also ...

Leg day is a staple in any well-rounded workout routine. And while many people make it a priority for a peachier backside or toned calves, strong legs are essential for reasons beyond aesthetics. In ...

Stretching and strengthening lower leg muscles can ease shin splint pain. Rest, ice, and low-impact exercise help recovery. See a doctor if pain or swelling doesn’t improve. Pain from shin splints can ...

He explains that metformin helps muscle cells better remodel and repair tissue during periods of recovery after inactivity. “Our real goal is to have patients maintain their muscle mass and function ...