Loop diuretics are widely used in the management of edema and heart failure. They are also widely misunderstood. The reason is this: Loop diuretics are often prescribed in a dose-dependent strategy.

Loop diuretics are widely used, especially in patients with hypertension or heart failure plus renal dysfunction. Such patients are particularly susceptible to untoward drug effects. It is, therefore, ...

Dietary sodium restriction is a key determinant of diuretic efficacy. When dietary sodium intake is high, postdiuretic sodium retention compensates almost entirely for the loop-diuretic-induced sodium ...

Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Please provide your email address to receive an email when new articles are posted on . There was no link found between ever use of loop diuretics and changes in bone mineral density, falls and ...

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...