The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

HIV-seq identifies key differences in HIV-infected cells before and after starting antiretroviral therapy to support treatment research.

On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...

University of Delaware professor Juan Perilla (right), is co-author of a new paper that reveals a previously unknown structural role for integrase, a key HIV protein, earlier in the virus' life cycle ...

Victor Appay, PhD, explains how long-term ART slows immune aging, boosting HIV viral suppression and paving the way for ...

I see that ViroLogic now offers information on the replicative capacity of patient virus, alongside information on its genotypic and phenotypic resistance profile. How should we use this information ...

CD8 T lymphocytes from immunologically stable HIV-1-infected secrete a soluble factor — termed CAF —, which suppresses HIV-1 replication, but the exact identity of CAF has been unclear. In September ...

Melissa Schnure, PhD, wants to make sure some of the country’s most vulnerable patients are protected — low-income people living with HIV who depend on federally funded HIV services.It is why Schnure, ...