This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

Epigenetics, the study of changes in gene expression that are not caused by alterations in the DNA sequence, has emerged as a key player in the development and severity of type 2 diabetes. Epigenetics ...

Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected ...

Salt stress remains a critical challenge for plant growth, especially in crops like pea (Pisum sativum L.). This study explores the role of histone modifications in regulating pea's response to salt ...

ASH1, Absent, small, or homeotic discs 1; CpG, 5′-Cyto- sine-phosphate-Guanine-3′ EZH, Enhancer of Zeste Homolog; GAS5, growth arrest-specific transcript 5; IFT80, Intraflagellar Transport 80; ...

A research team has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division.

Our group has contributed to the molecular and functional understanding of histone mark and DNA methylation mark readout by writer, reader and eraser proteins, as well as investigated the crosstalk ...

Epigenetics is the study of the impact of human lifestyle and environmental factors on gene expression patterns. Epigenetic changes are dynamic and reversible and inherited somatically. These changes ...

New research in C. elegans from scientists at Howard Hughes Medical Institute (HHMI) helps explain how changes in the parents’ lysosomes that promote longevity are transferred to their offspring.