Accurate RNA splicing is essential for gene expression and human health, yet predicting how DNA sequence variations affect ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able to fill such disparate niches because molecular machinery can cut out and ...

Scientists at the Hospital for Sick Children (SickKids) and the University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition ...

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome—the working portion of our DNA that helps make each person ...

“Interestingly, the Alzheimer’s field has long believed that nitric oxide levels were too high and contributed to the disease,” Dr. Stamler said. “This new discovery changes that paradigm.” ...