Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how the system consistently produces highly effective antibodies. The findings overturn longstanding ...

Example of a spatial configuration of a 2D expanding and evolving colony of cells, a typical simulation representing an example with 3 mutations. The individual graphs represent different snapshots in ...

Cancer does not develop overnight. It can take decades for cancer-promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...

Available in electronic full text to members of the University via the Library web catalogue. ELEC copy purchased with funds from the S. Dillon Ripley Endowment A fundamental and groundbreaking ...

"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." It sounds like a cyberpunk vision. Inspired by the generative abilities of AI, directed evolution, a ...

New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Germinal centers are high-speed evolution ...

The problem of how life evolved on Earth has intrigued the minds of many great scientists for centuries. Now, according to an exciting study published in the Proceedings of the National Academy of ...

Thought too hard to do, a new platform evolved proteins in mammalian cells, which could help researchers design drugs that work better in humans. “There are many, many examples, both published and ...