Proteins are the molecular workhorses of cells. To understand their functions, scientists soon realized that they had to figure out proteins’ shapes. But solving a protein structure is a challenging ...

An international research team led by a Korean scientist has succeeded in designing large-scale protein structures that ...

The known protein universe just got a lot bigger. A newly released artificial-intelligence tool has generated an atlas of more than one billion predicted protein structures and billions more protein ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

Protein-ligand docking is an established tool in drug discovery and development to narrow down potential therapeutics for experimental testing. However, a high-quality protein structure is required ...

Proteins play diverse roles in all domains of life and are extensively harnessed as biomolecules in biotechnology, with applications spanning from fundamental research to biomedicine. Therefore, there ...

The 2024 Nobel prize in chemistry has been awarded to David Baker, Demis Hassabis and John Jumper for their work on understanding the structure of proteins, which play vital roles in all living ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Illustration showing how integrating protein three-dimensional structures with artificial intelligence algorithms can predict synergistic or antagonistic effects of drug combinations, guiding safer ...

Scientists from Scripps Research have uncovered new structures of transthyretin, a protein that moves important hormones like thyroxine through blood and spinal fluid. Misfolded versions of the ...