WASHINGTON − President Donald Trump threatened Iran's supreme leader with assassination as he pushed Tehran to give up its nuclear enrichment program and air strikes continued over Iran and Israel.

President Trump said early Tuesday morning that he wants "a real end" to Iran's nuclear problem, with Tehran "giving up entirely" its enrichment activities. He said he was not just working toward a ceasefire to end the war between Iran and Israel,

Iran should have signed the ‘deal’ I told them to sign,” Trump posted on Truth Social. “What a shame, and waste of human life. Simply stated, IRAN CAN NOT HAVE A NUCLEA

President Trump said in a social-media post that Tehran has lost control of Iran’s airspace. “We now have complete and total control of the skies over Iran,” Trump wrote. “Iran had good sky trackers and other defensive equipment,

Trump arrived at the White House early Tuesday at a moment of choosing in his presidency. Israel, with five days of missile strikes, has done considerable damage to Iran and believes it can now deal a permanent blow to Tehran’s nuclear program — particularly if it gets a little more help from the Republican president.

Iranian officials have warned that U.S. participation in an attack on its facilities will imperil any chance of the nuclear disarmament deal the president insists he is still interested in pursuing.

After canceling negotiations with the U.S. scheduled for Sunday, Tehran has signaled it is willing to talk.

The Trump administration has attempted to negotiate a nuclear deal with Iran in recent months but talks halted after Israel struck Tehran last week. “Iran should have signed the