Adrian Houser combined with four relievers to shutout the Mariners last night, 1-0. Seattle managed just four hits off the Sox hurlers.

Matt Thaiss started the fourth with a leadoff single. After Luis Robert Jr. struck out, Lenyn Sosa connected on a changeup out of the zone for a two-run homer to tie the game at 3-3. In the next at-bat, Joshua Palacios hit a fly ball to right field for a solo homer to give the Sox their first lead at 4-3.

See all the player props bets with current odds for the MLB matchup between the Seattle Mariners and White Sox on }{ day_of_week model.date }}, May 21,

CHICAGO - The Seattle Mariners defeated the Chicago White Sox 6-5 on Wednesday afternoon at Rate Field, moving to 28-20 on the season. The M's continue to pace

The Seattle Mariners will look to bounce back from their second shutout loss of the season when they bid to secure a road series victory from the Chicago White Sox on Wednesday afternoon.

MLB player prop bets and odds for Chase Meidroth on Wednesday, May 21, 2025, as the Chicago White Sox take on the Seattle Mariners.

After a lengthy rain delay to start the game, the Mariners are held to just four hits and fall to the White Sox 1-0 on a chilly night in Chicago, snapping a four-game win streak.

Preview the May 21 matchup between the Seattle Mariners and Chicago White Sox with odds over/under, game spread, betting lines and more.

Matt Thaiss has been a steady presence behind the plate, and the Sox' No. 2 prospect, Kyle Teel, is knocking on the door from Triple-A Charlotte.